SLC50A1

Across TCGA patient cohorts, SLC50A1 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC50A1-associated genes across cancer lineages are RNA5SP536, TBC1D3F, and P3R3URF-PIK3R3. Each is linked with SLC50A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC50A1-to-partner and partner-to-SLC50A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP536 grouped by SLC50A1-low versus SLC50A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC50A1→partner) and Y-score (partner→SLC50A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP536 →	+0.249	+4.137	<.001	.008	3	1
UCEC	TBC1D3F →	+0.028	+3.233	.007	.002	3	1
SKCM	P3R3URF-PIK3R3 →	+0.035	+6.199	<.001	.001	3	1
UCEC	PPIAP7 →	+0.293	+4.384	<.001	<.001	3	1
COAD	RNU6-929P →	+0.368	+7.741	<.001	.009	3	1
SKCM	KIF3AP1 →	+0.086	+5.292	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

RNA5SP536 by SLC50A1 expression — UCEC

Explore this box plot interactively →