SLC4A4

Across TCGA patient cohorts, SLC4A4 protein abundance is significantly associated with the RNA expression of many other genes, with 14,623 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC4A4-associated genes across cancer lineages are LDHAL6EP, ATP13A4, and KNSTRN. Each is linked with SLC4A4 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC4A4-to-partner and partner-to-SLC4A4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC4A4 versus LDHAL6EP in UCEC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A4→partner) and Y-score (partner→SLC4A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LDHAL6EP →	+1.659	+1.716	.006	.007	3	6
GBM	ATP13A4 →	+1.554	+0.684	<.001	<.001	3	4
LSCC	KNSTRN →	-0.703	-0.607	<.001	.001	3	4
LSCC	RGN →	+0.758	+0.573	<.001	<.001	3	4
GBM	FAM189A2 →	+0.925	+0.436	.001	.003	3	4
LUAD	HABP2 →	+1.504	+0.578	.003	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,623 associations by consensus.

SLC4A4 vs LDHAL6EP — UCEC

Explore this scatter interactively →