SLC4A2

Across TCGA patient cohorts, SLC4A2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,614 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SLC4A2-associated genes across cancer lineages are RHOBTB3, HSPD1P11, and SOX4. Each is linked with SLC4A2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC4A2-to-partner and partner-to-SLC4A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC4A2 versus RHOBTB3 in BRCA, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A2→partner) and Y-score (partner→SLC4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RHOBTB3 →	-1.425	-0.476	<.001	<.001	3	5
UCEC	HSPD1P11 →	-1.132	-0.563	<.001	<.001	3	5
PDAC	SOX4 →	-0.767	-0.464	<.001	<.001	3	3
BRCA	SRRM3 →	-0.766	-0.337	.005	<.001	2	4
PDAC	APCDD1L-DT →	-0.881	-0.612	<.001	<.001	3	3
PDAC	HOXB-AS2 →	-0.632	-0.476	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,614 associations by consensus.

SLC4A2 vs RHOBTB3 — BRCA

Explore this scatter interactively →