SLC4A1AP

Across TCGA pan-cancer cohorts, SLC4A1AP Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC4A1AP data layer compared with 20 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher SLC4A1AP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLC4A1AP expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

SKCM, UCEC, and STAD are the cancer types where SLC4A1AP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.347	0.784	.007	12	view →
UCEC	DFS	Median	All	0.955	0.619	.017	8	view →
STAD	OS	Median	III,IV	0.169	0.641	.001	6	view →
BLCA	OS	Median	III,IV	1.000	0.533	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC4A1AP–SKCM (OS)

Open the SKCM breakdown →