SLC4A1AP

Across TCGA pan-cancer cohorts, SLC4A1AP mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC4A1AP data layer compared with 20 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC4A1AP mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC4A1AP expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

CCRCC, PDAC, and LSCC are the cancer types where SLC4A1AP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	III,IV	0.582	1.000	<.001	34	view →
PDAC	DFS	Quartile	III,IV	0.493	0.890	.011	26	view →
LSCC	DFS	Quartile	All	1.000	0.859	.006	9	view →
HNSC	DFS	Tertile	IV	0.731	0.921	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC4A1AP–CCRCC (OS)

Open the CCRCC breakdown →