SLC4A1AP

mass-spec protein — tumor vs normal
Tumor vs Normalmass-specBox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC4A1AP mass-spec protein differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SLC4A1AP’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SLC4A1AP mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types SLC4A1AP is over-expressed in tumor.

COAD, CCRCC, and HNSC are the cancer types where SLC4A1AP tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC4A1AP mass-spec protein (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADMaleIII,IV+0.503<.00112view →
CCRCCAllIV+0.185<.00112view →
HNSCMaleIV+0.476<.00111view →
LUADMaleIII,IV+0.415<.0019view →
LSCCFemaleII,III,IV+0.638<.0018view →
OVAllAll+0.354.0112view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

SLC4A1AP–COAD

Tumor-vs-normal mass-spec protein box plot for SLC4A1AP in COAD.

Open the COAD breakdown →

Exploration