SLC4A11

Across TCGA patient cohorts, SLC4A11 protein abundance is significantly associated with the RNA expression of many other genes, with 7,388 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC4A11-associated genes across cancer lineages are PTCD1, TCF20, and TTLL12. Each is linked with SLC4A11 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC4A11-to-partner and partner-to-SLC4A11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC4A11 versus PTCD1 in HNSC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A11→partner) and Y-score (partner→SLC4A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PTCD1 →	+0.482	+0.556	.001	.001	3	3
LSCC	TCF20 →	+0.534	+0.590	<.001	<.001	3	2
LSCC	TTLL12 →	+0.991	+0.894	<.001	<.001	3	2
HNSC	BMP7 →	+2.078	+0.666	<.001	.001	3	2
LSCC	ASIP →	+0.787	+0.628	<.001	<.001	3	2
LSCC	ADNP2 →	+0.441	+0.633	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,388 associations by consensus.

SLC4A11 vs PTCD1 — HNSC

Explore this scatter interactively →