SLC4A11

Across TCGA cell cohorts, SLC4A11 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,928 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC4A11-associated GO terms across cancer lineages are Positive regulation of protein localization to endoplasmic reticulum, Regulation of protein localization to endoplasmic reticulum, and Regulation of plasma cell differentiation. Each is linked with SLC4A11 in more than 12 cancer types. Because this analysis shows association rather than direction, both SLC4A11-to-partner and partner-to-SLC4A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to endoplasmic reticulum grouped by SLC4A11-low versus SLC4A11-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A11→partner) and Y-score (partner→SLC4A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of protein localization to endoplasmic reticulum →	+0.162	+2.303	<.001	<.001	3	13
OESOPHAGUS	Regulation of protein localization to endoplasmic reticulum →	+0.168	+2.228	<.001	<.001	3	11
OESOPHAGUS	Regulation of plasma cell differentiation →	+0.188	+1.825	<.001	.002	3	10
OESOPHAGUS	Positive regulation of plasma cell differentiation →	+0.177	+1.705	<.001	.003	3	9
BREAST	Regulation of mesenchymal stem cell differentiation →	+0.115	+1.394	<.001	<.001	3	9
SOFT_TISSUE	Protein localization to cytoplasmic stress granule →	+0.087	+1.541	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,928 associations by consensus.

Positive regulation of protein localization to endoplasmic reticulum by SLC4A11 expression — OESOPHAGUS

Explore this box plot interactively →