SLC4A11

Across TCGA cell cohorts, SLC4A11 mutation is significantly associated with the RNA expression of many other genes, with 583 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC4A11-associated genes across cancer lineages are IFNA14, MTFMT, and NUP43. Each is linked with SLC4A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC4A11-to-partner and partner-to-SLC4A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA14 grouped by SLC4A11-low versus SLC4A11-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A11→partner) and Y-score (partner→SLC4A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IFNA14 →	+0.032	+5.369	<.001	.004	3	2
LARGE_INTESTINE	MTFMT →	+0.615	+3.459	<.001	.001	3	2
LARGE_INTESTINE	NUP43 →	+0.580	+2.628	<.001	.002	3	2
LARGE_INTESTINE	CYP4V2 →	+1.070	+3.169	.001	.009	3	2
LARGE_INTESTINE	CCNB3 →	+0.680	+3.526	<.001	<.001	3	2
LARGE_INTESTINE	PRMT9 →	+0.433	+2.628	.008	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 583 associations by consensus.

IFNA14 by SLC4A11 expression — SOFT_TISSUE

Explore this box plot interactively →