SLC4A10

Across TCGA patient cohorts, SLC4A10 mutation is significantly associated with the RNA expression of many other genes, with 4,007 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC4A10-associated genes across cancer lineages are DRG1, CCT7, and TXNL4A. Each is linked with SLC4A10 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC4A10-to-partner and partner-to-SLC4A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DRG1 grouped by SLC4A10-low versus SLC4A10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A10→partner) and Y-score (partner→SLC4A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DRG1 →	+0.294	+1.649	<.001	<.001	3	4
UCEC	CCT7 →	+0.357	+1.810	<.001	.001	3	4
UCEC	TXNL4A →	+0.349	+1.627	<.001	<.001	3	4
UCEC	TIMM21 →	+0.359	+2.169	.001	.002	3	4
UCEC	PTP4A3 →	-0.703	-3.311	<.001	<.001	3	3
UCEC	LONP1 →	+0.725	+2.513	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,007 associations by consensus.

DRG1 by SLC4A10 expression — UCEC

Explore this box plot interactively →