SLC4A10

Across TCGA pan-cancer cohorts, SLC4A10 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of SLC4A10’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SLC4A10 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC4A10 is over-expressed in tumor, although a few such as COAD and LUSC show the opposite, repressed pattern.

COAD, LUSC, and KICH are the cancer types where SLC4A10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC4A10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	−1.448	<.001	11	view →
LUSC	All	III,IV	−0.201	<.001	7	view →
KICH	All	All	−0.055	.002	6	view →
READ	All	II,III,IV	−1.195	<.001	5	view →
KIRP	All	All	+0.259	.002	5	view →
KIRC	Male	All	+0.164	<.001	4	view →
UCEC	All	All	−0.152	.036	4	view →
BLCA	Male	IV	−0.062	.001	2	view →
STAD	Male	II,III,IV	−0.117	.036	1	view →
LIHC	All	All	−0.059	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

SLC4A10–COAD

Open the COAD breakdown →