SLC4A10

Across TCGA patient cohorts, SLC4A10 mutation is significantly associated with the total protein of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC4A10-associated genes across cancer lineages are p62 Lck ligand, PKC-delta_pS664, and Rictor_pT1135. Each is linked with SLC4A10 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC4A10-to-partner and partner-to-SLC4A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by SLC4A10-low versus SLC4A10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A10→partner) and Y-score (partner→SLC4A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.337	+1.754	<.001	.001	3	3
COAD	PKC-delta_pS664 →	-0.146	-3.450	.015	.005	3	2
COAD	Rictor_pT1135 →	-0.125	-2.296	.041	.035	3	2
COAD	Caspase-7-cleavedD198 →	+1.402	+2.330	<.001	.020	2	3
UCEC	FASN →	+0.302	+1.584	.011	.017	3	2
UCEC	FoxM1 →	+0.161	+1.321	.039	.012	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

p62 Lck ligand by SLC4A10 expression — UCEC

Explore this box plot interactively →