SLC4A10

Across TCGA cell cohorts, SLC4A10 mutation is significantly associated with the RNA expression of many other genes, with 261 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC4A10-associated genes across cancer lineages are LRRC74A, POMGNT2, and BANF2. Each is linked with SLC4A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC4A10-to-partner and partner-to-SLC4A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRRC74A grouped by SLC4A10-low versus SLC4A10-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A10→partner) and Y-score (partner→SLC4A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	LRRC74A →	+0.069	+4.269	.003	.005	3	2
LARGE_INTESTINE	POMGNT2 →	+0.986	+3.212	<.001	.006	3	2
OESOPHAGUS	BANF2 →	+0.146	+4.906	<.001	.006	3	1
OESOPHAGUS	MS4A6E →	+0.050	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUSC	SLC2A7 →	+0.013	+4.643	<.001	.008	3	1
SKIN	H2BW2 →	+0.066	+2.882	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 261 associations by consensus.

LRRC74A by SLC4A10 expression — LUNG_SCLC

Explore this box plot interactively →