SLC49A4

Across TCGA patient cohorts, SLC49A4 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,748 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC49A4-associated proteins across cancer lineages are GSK3B, HSPBAP1, and UMPS. Each is linked with SLC49A4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC49A4-to-partner and partner-to-SLC49A4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC49A4 versus GSK3B in LSCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC49A4→partner) and Y-score (partner→SLC49A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GSK3B →	+0.306	+0.434	<.001	<.001	3	4
HNSC	HSPBAP1 →	+0.401	+0.739	<.001	<.001	3	4
LSCC	UMPS →	+0.439	+0.664	<.001	<.001	3	4
COAD	SUGT1 →	-0.241	-0.371	.005	<.001	3	4
GBM	NIT2 →	+0.272	+0.261	<.001	.001	3	4
LSCC	PIK3CA →	+0.315	+0.603	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,748 associations by consensus.

SLC49A4 vs GSK3B — LSCC

Explore this scatter interactively →