SLC49A4

Across TCGA cell cohorts, SLC49A4 mutation is significantly associated with the drug of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC49A4-associated genes across cancer lineages are NSC-207895, PF-00299804, and ZL109. Each is linked with SLC49A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC49A4-to-partner and partner-to-SLC49A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NSC-207895 grouped by SLC49A4-low versus SLC49A4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC49A4→partner) and Y-score (partner→SLC49A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NSC-207895 →	+0.491	+2.691	.023	.032	3	1
LARGE_INTESTINE	PF-00299804 →	+0.544	+2.652	.020	.045	3	1
LARGE_INTESTINE	ZL109 →	-0.336	-2.743	.034	.046	2	1
LARGE_INTESTINE	SB505124 →	-0.536	-2.743	.014	.046	1	1
LARGE_INTESTINE	123829 →	+0.575	+2.649	.049	.046	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

NSC-207895 by SLC49A4 expression — LARGE_INTESTINE

Explore this box plot interactively →