SLC49A3

Across TCGA pan-cancer cohorts, SLC49A3 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC49A3 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC49A3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLC49A3 expression acts as an unfavorable survival marker.

LUAD, KIRC, and COAD are the cancer types where SLC49A3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.057	0.788	<.001	18	view →
KIRC	OS	Median	All	0.127	0.874	<.001	12	view →
COAD	DFS	Median	All	0.149	0.691	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC49A3–LUAD (OS)

Open the LUAD breakdown →