SLC49A3

Across TCGA patient cohorts, SLC49A3 protein abundance is significantly associated with the RNA expression of many other genes, with 469 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SLC49A3-associated genes across cancer lineages are FKBP3, COCH, and PSMC6. Each is linked with SLC49A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC49A3-to-partner and partner-to-SLC49A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC49A3 versus FKBP3 in BRCA, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC49A3→partner) and Y-score (partner→SLC49A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FKBP3 →	+0.679	+1.876	<.001	.001	3	1
BRCA	COCH →	-1.747	-1.982	.005	.002	3	1
BRCA	PSMC6 →	+0.426	+1.587	.006	.009	3	1
BRCA	GNPNAT1 →	+0.646	+1.371	.004	<.001	3	1
BRCA	SPTLC2 →	+0.791	+1.095	.006	.008	3	1
BRCA	GSKIP →	+0.479	+1.203	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 469 associations by consensus.

SLC49A3 vs FKBP3 — BRCA

Explore this scatter interactively →