SLC49A3

Across TCGA patient cohorts, SLC49A3 mutation is significantly associated with the immune_cell of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC49A3-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tcm, and MSC. Each is linked with SLC49A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC49A3-to-partner and partner-to-SLC49A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by SLC49A3-low versus SLC49A3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC49A3→partner) and Y-score (partner→SLC49A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.017	+2.622	.009	.022	3	1
UCEC	CD8+ Tcm →	+0.035	+2.713	<.001	.018	3	1
UCEC	MSC →	-0.321	-3.169	.005	.020	3	1
UCEC	CD4+ memory T-cells →	+0.019	+2.148	.046	.019	3	1
UCEC	Th2 cells →	+0.268	+3.169	.006	.020	3	1
UCEC	CD4+ T-cells →	+0.006	+4.896	<.001	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

CD8+ T-cells by SLC49A3 expression — UCEC

Explore this box plot interactively →