SLC49A3

Across TCGA cell cohorts, SLC49A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,941 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC49A3-associated GO terms across cancer lineages are Positive regulation of ligase activity, Regulation of plasma membrane bounded cell projection assembly, and Positive regulation of protein transport. Each is linked with SLC49A3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC49A3-to-partner and partner-to-SLC49A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of ligase activity grouped by SLC49A3-low versus SLC49A3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC49A3→partner) and Y-score (partner→SLC49A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of ligase activity →	-0.085	-0.611	.001	<.001	3	7
OESOPHAGUS	Regulation of plasma membrane bounded cell projection assembly →	+0.060	+0.702	<.001	<.001	3	7
OESOPHAGUS	Positive regulation of protein transport →	+0.063	+0.585	<.001	.002	3	7
OESOPHAGUS	Regulation of cell projection assembly →	+0.039	+0.642	.002	<.001	3	7
OESOPHAGUS	Protein localization to membrane →	+0.039	+0.587	.001	.001	3	7
LUNG_NSCLC_LUAD	Negative regulation of actin filament polymerization →	+0.085	+0.675	<.001	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,941 associations by consensus.

Positive regulation of ligase activity by SLC49A3 expression — OESOPHAGUS

Explore this box plot interactively →