SLC47A1

Across TCGA cell cohorts, SLC47A1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SLC47A1-associated genes across cancer lineages are LY6G6F, AVP, and PRAMEF2. Each is linked with SLC47A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC47A1-to-partner and partner-to-SLC47A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LY6G6F grouped by SLC47A1-low versus SLC47A1-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC47A1→partner) and Y-score (partner→SLC47A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	LY6G6F →	+0.036	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUAD	AVP →	+0.044	+3.734	<.001	.006	3	1
LUNG_NSCLC_LUAD	PRAMEF2 →	+0.015	+3.734	<.001	.006	3	1
LUNG_NSCLC_LUAD	MT1B →	+0.422	+3.760	.001	.008	3	1
LUNG_NSCLC_LUAD	VN1R2 →	+0.041	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	IQCF5 →	+0.045	+4.189	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

LY6G6F by SLC47A1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →