SLC46A3

Across TCGA cell cohorts, SLC46A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,123 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC46A3-associated GO terms across cancer lineages are Interleukin-10-mediated signaling pathway, Protein deglycosylation, and Endoplasmic reticulum mannose trimming. Each is linked with SLC46A3 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC46A3-to-partner and partner-to-SLC46A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interleukin-10-mediated signaling pathway grouped by SLC46A3-low versus SLC46A3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC46A3→partner) and Y-score (partner→SLC46A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Interleukin-10-mediated signaling pathway →	+0.225	+1.502	.001	.004	3	10
BONE	Protein deglycosylation →	+0.119	+1.402	.003	.002	3	10
LUNG_NSCLC_LUSC	Endoplasmic reticulum mannose trimming →	+0.095	+2.144	.002	<.001	2	10
BONE	Protein demannosylation →	+0.107	+1.106	.004	.005	3	9
BONE	Protein alpha-1,2-demannosylation →	+0.107	+1.106	.004	.005	3	9
CNS	Golgi vesicle transport →	+0.061	+1.444	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,123 associations by consensus.

Interleukin-10-mediated signaling pathway by SLC46A3 expression — BONE

Explore this box plot interactively →