SLC45A4

Across TCGA patient cohorts, SLC45A4 mutation is significantly associated with the RNA expression of many other genes, with 3,552 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC45A4-associated genes across cancer lineages are TUBGCP5, HP1BP3, and CDCA2. Each is linked with SLC45A4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC45A4-to-partner and partner-to-SLC45A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TUBGCP5 grouped by SLC45A4-low versus SLC45A4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC45A4→partner) and Y-score (partner→SLC45A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TUBGCP5 →	+0.370	+1.526	<.001	.001	3	4
SKCM	HP1BP3 →	+0.450	+1.925	.006	.009	3	4
COAD	CDCA2 →	+0.926	+3.472	<.001	.002	3	4
UCEC	CASP3 →	+0.435	+1.688	<.001	<.001	3	4
SKCM	SAAL1 →	+0.439	+2.434	.006	.001	3	4
COAD	DEPDC1 →	+0.910	+3.499	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,552 associations by consensus.

TUBGCP5 by SLC45A4 expression — UCEC

Explore this box plot interactively →