SLC44A5

Across TCGA patient cohorts, SLC44A5 mutation is significantly associated with the RNA expression of many other genes, with 3,120 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC44A5-associated genes across cancer lineages are PRC1, PHC2-AS1, and INCENP. Each is linked with SLC44A5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC44A5-to-partner and partner-to-SLC44A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRC1 grouped by SLC44A5-low versus SLC44A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A5→partner) and Y-score (partner→SLC44A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRC1 →	+0.686	+1.807	<.001	<.001	3	4
LUSC	PHC2-AS1 →	+0.297	+3.369	.007	.004	3	4
UCEC	INCENP →	+0.527	+1.882	.001	.001	3	4
COAD	PKN3 →	+0.825	+3.335	<.001	.005	3	4
UCEC	GCN1 →	+0.436	+1.797	<.001	.007	3	4
UCEC	DHRS2 →	+1.139	+2.072	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,120 associations by consensus.

PRC1 by SLC44A5 expression — UCEC

Explore this box plot interactively →