SLC44A4

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC44A4 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC44A4-associated genes across cancer lineages are Notch1, eIF4E, and A-Raf_pS299. Each is linked with SLC44A4 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC44A4-to-partner and partner-to-SLC44A4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A4→partner) and Y-score (partner→SLC44A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNotch1 →+0.163+2.128.001.00933
UCECeIF4E →+0.224+2.906.002.00132
UCECA-Raf_pS299 →-0.115-2.321.006.00532
UCECJNK_pT183_Y185 →-0.176-2.321.003.00532
UCECmTOR_pS2448 →-0.144-1.662.006.01132
UCECAkt_pT308 →+0.540+3.321.015.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration