Across TCGA cell cohorts, SLC44A4 mutation is significantly associated with the mutation status of many other genes, with 3,799 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC44A4-associated genes across cancer lineages are MYBPC3, CDH12, and ATP2A3. Each is linked with SLC44A4 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC44A4-to-partner and partner-to-SLC44A4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A4→partner) and Y-score (partner→SLC44A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MYBPC3 →	+5.000	+4.187	.008	.008	1	5
SOFT_TISSUE	CDH12 →	+5.066	+4.502	.007	.007	1	5
LUNG_NSCLC_LUAD	ATP2A3 →	+4.000	+4.303	.001	.001	1	4
BREAST	NLRP8 →	+4.297	+4.857	.009	.009	1	4
CNS	MUC17 →	+2.371	+4.127	.004	.004	1	4
LUNG_NSCLC_LUAD	TSC2 →	+3.263	+3.851	.005	.005	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,799 associations by consensus.

Exploration

SLC44A4 survival (RNA) · tumor vs normal (RNA) · all SLC44A4 data types