SLC44A4

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC44A4 mutation is significantly associated with the drug of many other genes, with 27 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC44A4-associated genes across cancer lineages are Mirin, 5-Fluorouracil, and NSC-207895. Each is linked with SLC44A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC44A4-to-partner and partner-to-SLC44A4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A4→partner) and Y-score (partner→SLC44A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEMirin →+0.468+2.868.008.02231
LARGE_INTESTINE5-Fluorouracil →+0.597+2.991.030.01831
LARGE_INTESTINENSC-207895 →+0.483+2.710.018.02731
LARGE_INTESTINEkb NB 142-70 →+0.605+2.874.006.02131
LARGE_INTESTINEETP-45835 →+0.231+2.874.044.02131
LARGE_INTESTINEVinblastine →+0.978+2.655.023.04412
Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration