SLC44A1

Across TCGA patient cohorts, SLC44A1 mutation is significantly associated with the RNA expression of many other genes, with 3,691 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC44A1-associated genes across cancer lineages are MIR5580, RNU6-1213P, and MIR1245A. Each is linked with SLC44A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC44A1-to-partner and partner-to-SLC44A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5580 grouped by SLC44A1-low versus SLC44A1-high in SARC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A1→partner) and Y-score (partner→SLC44A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	MIR5580 →	+0.823	+5.477	<.001	.004	3	4
BRCA	RNU6-1213P →	+0.322	+5.649	<.001	.001	3	3
COAD	MIR1245A →	+0.492	+2.781	.007	.007	3	3
BRCA	SLC25A15P4 →	+0.237	+4.630	.008	.001	3	2
BRCA	OR4A5 →	+0.032	+6.140	<.001	<.001	3	2
BRCA	ST6GALNAC2P1 →	+0.076	+5.201	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,691 associations by consensus.

MIR5580 by SLC44A1 expression — SARC

Explore this box plot interactively →