SLC44A1

Across TCGA cell cohorts, SLC44A1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC44A1-associated genes across cancer lineages are LEUTX, S100A7A, and LGALS16. Each is linked with SLC44A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC44A1-to-partner and partner-to-SLC44A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LEUTX grouped by SLC44A1-low versus SLC44A1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A1→partner) and Y-score (partner→SLC44A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	LEUTX →	+0.226	+5.321	<.001	.005	3	1
BLOOD_Lymphoma	S100A7A →	+0.042	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	LGALS16 →	+0.087	+5.247	<.001	.001	3	1
LUNG_NSCLC_LUAD	SUPT20HL1 →	+0.006	+4.947	.001	.001	3	1
SKIN	KRTAP5-4 →	+0.101	+4.977	<.001	.007	3	1
LARGE_INTESTINE	SLC12A1 →	+0.068	+3.658	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

LEUTX by SLC44A1 expression — CNS

Explore this box plot interactively →