SLC43A3

Across TCGA patient cohorts, SLC43A3 mutation is significantly associated with the RNA expression of many other genes, with 891 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC43A3-associated genes across cancer lineages are SS18L2P1, FAM133GP, and MIR1269B. Each is linked with SLC43A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC43A3-to-partner and partner-to-SLC43A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SS18L2P1 grouped by SLC43A3-low versus SLC43A3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC43A3→partner) and Y-score (partner→SLC43A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SS18L2P1 →	+0.416	+2.695	<.001	.004	3	3
KIRP	FAM133GP →	+0.278	+4.409	<.001	.006	3	2
KIRP	MIR1269B →	+0.400	+4.928	<.001	.005	3	2
BRCA	TRIAP1P1 →	+0.156	+5.162	<.001	.004	3	2
UCEC	PHF5A →	+0.492	+4.247	.001	<.001	3	2
UCEC	CDADC1 →	+0.403	+3.740	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 891 associations by consensus.

SS18L2P1 by SLC43A3 expression — COAD

Explore this box plot interactively →