SLC39A9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC39A9 mutation is significantly associated with the RNA expression of many other genes, with 1,330 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A9-associated genes across cancer lineages are USP9YP2, SNRPCP20, and VN1R18P. Each is linked with SLC39A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A9-to-partner and partner-to-SLC39A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP9YP2 grouped by SLC39A9-low versus SLC39A9-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A9→partner) and Y-score (partner→SLC39A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAUSP9YP2 →+0.039+7.640<.001.00932
COADSNRPCP20 →+0.474+3.831<.001.00732
BRCAVN1R18P →+0.066+6.016<.001.00231
BRCAMIR3118-3 →+0.371+7.471<.001.00831
UCECCOPS8P1 →+0.066+1.994<.001.00231
UCECCCL5 →+1.125+2.716<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,330 associations by consensus.

USP9YP2 by SLC39A9 expression — BLCA

Box plot of USP9YP2 in SLC39A9-low vs SLC39A9-high samples in BLCA.

Explore this box plot interactively →

Exploration