SLC39A8

Across TCGA patient cohorts, SLC39A8 mutation is significantly associated with the RNA expression of many other genes, with 3,033 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A8-associated genes across cancer lineages are MTND1P6, RNU6-1138P, and LINC01997. Each is linked with SLC39A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A8-to-partner and partner-to-SLC39A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND1P6 grouped by SLC39A8-low versus SLC39A8-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A8→partner) and Y-score (partner→SLC39A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MTND1P6 →	+0.035	+4.758	<.001	.006	3	2
COAD	RNU6-1138P →	+0.442	+4.790	<.001	.006	3	2
LIHC	LINC01997 →	+0.092	+5.676	<.001	.001	3	2
STAD	NDUFA5P5 →	+0.195	+3.853	.007	.008	3	2
LUSC	FDX1P2 →	+0.213	+5.370	<.001	.001	3	2
LIHC	NF1P1 →	+0.016	+4.878	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,033 associations by consensus.

MTND1P6 by SLC39A8 expression — LIHC

Explore this box plot interactively →