SLC39A7

Across TCGA pan-cancer cohorts, SLC39A7 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC39A7 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SLC39A7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC39A7 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, UCEC, and CCRCC are the cancer types where SLC39A7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	IV	1.000	0.659	.003	28	view →
UCEC	OS	Median	All	0.932	1.000	.026	6	view →
CCRCC	OS	Median	IV	0.150	0.785	.040	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC39A7–HNSC (DFS)

Open the HNSC breakdown →