SLC39A7

Across TCGA patient cohorts, SLC39A7 mutation is significantly associated with the RNA expression of many other genes, with 1,252 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A7-associated genes across cancer lineages are LINC00428, TRAJ12, and TRDV1. Each is linked with SLC39A7 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC39A7-to-partner and partner-to-SLC39A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00428 grouped by SLC39A7-low versus SLC39A7-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A7→partner) and Y-score (partner→SLC39A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC00428 →	+0.240	+5.442	<.001	.002	3	4
BLCA	TRAJ12 →	+0.605	+3.799	.002	.007	3	2
UCEC	TRDV1 →	+0.838	+3.302	<.001	<.001	3	2
UCEC	TRAJ9 →	+0.557	+2.033	<.001	.001	3	2
UCEC	LINC01941 →	+0.026	+3.582	<.001	.001	3	2
UCEC	RPL12P34 →	+0.059	+2.109	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,252 associations by consensus.

LINC00428 by SLC39A7 expression — BRCA

Explore this box plot interactively →