SLC39A7

Across TCGA patient cohorts, SLC39A7 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A7-associated genes across cancer lineages are PRDX1, ATM, and Bax. Each is linked with SLC39A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A7-to-partner and partner-to-SLC39A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRDX1 grouped by SLC39A7-low versus SLC39A7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A7→partner) and Y-score (partner→SLC39A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRDX1 →	+0.195	+3.321	.022	.009	3	2
UCEC	ATM →	-0.488	-3.308	.009	.009	3	2
UCEC	Bax →	+0.354	+2.321	<.001	.006	3	2
UCEC	EGFR_pY1068 →	-0.275	-2.321	.007	.006	3	1
UCEC	ER-alpha_pS118 →	-0.375	-1.807	.011	.027	3	1
UCEC	ERK2 →	+0.233	+3.321	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

PRDX1 by SLC39A7 expression — UCEC

Explore this box plot interactively →