SLC39A7

Across TCGA cell cohorts, SLC39A7 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC39A7-associated genes across cancer lineages are CCDC195, OR4S2, and IQCF5. Each is linked with SLC39A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A7-to-partner and partner-to-SLC39A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC195 grouped by SLC39A7-low versus SLC39A7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A7→partner) and Y-score (partner→SLC39A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC195 →	+0.044	+4.467	.003	.004	3	1
STOMACH	OR4S2 →	+0.020	+5.285	<.001	.003	3	1
BLOOD_Leukemia	IQCF5 →	+0.124	+5.201	<.001	.006	3	1
BLOOD_Leukemia	C6 →	+0.201	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CCDC195 by SLC39A7 expression — LARGE_INTESTINE

Explore this box plot interactively →