SLC39A3

Across TCGA patient cohorts, SLC39A3 mutation is significantly associated with the RNA expression of many other genes, with 183 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible SLC39A3-associated genes across cancer lineages are RNU5E-9P, RNY4P27, and RNU6-701P. Each is linked with SLC39A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC39A3-to-partner and partner-to-SLC39A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5E-9P grouped by SLC39A3-low versus SLC39A3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A3→partner) and Y-score (partner→SLC39A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU5E-9P →	+0.251	+5.087	<.001	.002	3	3
UCEC	RNY4P27 →	+0.287	+4.453	<.001	.006	3	2
UCEC	RNU6-701P →	+0.411	+3.801	.003	.004	3	2
UCEC	TRAJ4 →	+0.964	+4.348	<.001	.001	3	2
SKCM	MIR5194 →	+0.266	+3.393	<.001	.003	3	2
SKCM	BSN-AS1 →	+0.076	+3.018	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 183 associations by consensus.

RNU5E-9P by SLC39A3 expression — COAD

Explore this box plot interactively →