SLC39A2

Across TCGA patient cohorts, SLC39A2 mutation is significantly associated with the RNA expression of many other genes, with 1,122 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A2-associated genes across cancer lineages are RAD51, RNA5SP264, and TOMM22P2. Each is linked with SLC39A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A2-to-partner and partner-to-SLC39A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51 grouped by SLC39A2-low versus SLC39A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A2→partner) and Y-score (partner→SLC39A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD51 →	+0.849	+3.467	<.001	.002	3	2
LUAD	RNA5SP264 →	+0.474	+5.712	<.001	.003	3	2
LUAD	TOMM22P2 →	+0.466	+5.279	<.001	.006	3	2
LUAD	OR7K1P →	+0.078	+6.197	<.001	.001	3	2
THCA	TRIM60P3Y →	+0.064	+7.962	<.001	.007	3	1
THCA	RNA5SP471 →	+0.334	+7.962	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,122 associations by consensus.

RAD51 by SLC39A2 expression — UCEC

Explore this box plot interactively →