SLC39A2

Across TCGA cell cohorts, SLC39A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,092 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible SLC39A2-associated GO terms across cancer lineages are Negative regulation of mast cell degranulation, Positive regulation of proteolysis, and NMDA selective glutamate receptor signaling pathway. Each is linked with SLC39A2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC39A2-to-partner and partner-to-SLC39A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mast cell degranulation grouped by SLC39A2-low versus SLC39A2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A2→partner) and Y-score (partner→SLC39A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of mast cell degranulation →	+1.365	+1.485	.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Positive regulation of proteolysis →	+0.113	+1.715	<.001	<.001	3	7
URINARY_TRACT	NMDA selective glutamate receptor signaling pathway →	+0.268	+1.236	<.001	<.001	3	7
URINARY_TRACT	Response to indole-3-methanol →	+0.243	+1.203	<.001	<.001	3	7
BREAST	T cell mediated cytotoxicity →	+0.140	+0.914	.003	.004	3	6
BREAST	Establishment or maintenance of apical/basal cell polarity →	+0.075	+0.653	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,092 associations by consensus.

Negative regulation of mast cell degranulation by SLC39A2 expression — URINARY_TRACT

Explore this box plot interactively →