SLC39A2

Across TCGA cell cohorts, SLC39A2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC39A2-associated genes across cancer lineages are SLC15A5, OR10H5, and SYCN. Each is linked with SLC39A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A2-to-partner and partner-to-SLC39A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC15A5 grouped by SLC39A2-low versus SLC39A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A2→partner) and Y-score (partner→SLC39A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC15A5 →	+0.017	+4.415	<.001	.007	3	1
BLOOD_Leukemia	OR10H5 →	+0.070	+4.922	<.001	.009	3	1
BLOOD_Leukemia	SYCN →	+0.047	+5.539	<.001	.003	3	1
BLOOD_Leukemia	USP17L3 →	+0.012	+4.922	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SLC15A5 by SLC39A2 expression — LARGE_INTESTINE

Explore this box plot interactively →