SLC39A14

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC39A14 mutation is significantly associated with the RNA expression of many other genes, with 2,108 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A14-associated genes across cancer lineages are RNU1-17P, OR51A7, and MIR3922. Each is linked with SLC39A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A14-to-partner and partner-to-SLC39A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by SLC39A14-low versus SLC39A14-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A14→partner) and Y-score (partner→SLC39A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU1-17P →+0.460+5.688<.001<.00132
UCECOR51A7 →+0.064+1.773.006.00532
SKCMMIR3922 →+0.285+4.282<.001.00932
CESCNUTF2P8 →+0.118+5.144<.001.00332
UCECRNU4-58P →+0.196+2.326<.001.00132
UCECRN7SL447P →+0.138+1.904<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,108 associations by consensus.

RNU1-17P by SLC39A14 expression — CESC

Box plot of RNU1-17P in SLC39A14-low vs SLC39A14-high samples in CESC.

Explore this box plot interactively →

Exploration