SLC39A13

Across TCGA patient cohorts, SLC39A13 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A13-associated genes across cancer lineages are eIF4E, ERK2, and JNK2. Each is linked with SLC39A13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A13-to-partner and partner-to-SLC39A13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by SLC39A13-low versus SLC39A13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A13→partner) and Y-score (partner→SLC39A13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.199	+3.472	.011	.002	3	1
UCEC	ERK2 →	+0.192	+3.169	.007	.018	3	1
UCEC	JNK2 →	+0.225	+1.763	.002	.048	3	1
UCEC	mTOR →	-0.176	-1.415	.003	.046	3	1
UCEC	Notch1 →	+0.174	+3.817	<.001	<.001	3	1
UCEC	p62 Lck ligand →	+0.387	+2.125	.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

eIF4E by SLC39A13 expression — UCEC

Explore this box plot interactively →