SLC39A13

Across TCGA pan-cancer cohorts, SLC39A13 RNA is linked to patient survival in 30 of 34 cancer types, making it the most broadly survival-associated SLC39A13 data layer compared with 6 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher SLC39A13 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SLC39A13 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

MESO, LUSC, and LIHC are the cancer types where SLC39A13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.254	0.501	<.001	123	view →
LUSC	DFS	Tertile	II,III,IV	0.296	0.553	<.001	97	view →
LIHC	DFS	Median	All	0.473	0.609	<.001	71	view →
COAD	DFS	Quartile	All	0.716	0.846	.001	56	view →
UVM	DFS	Median	All	0.398	0.904	<.001	53	view →
CESC	DFS	Tertile	All	0.636	0.849	<.001	44	view →
LGG	DFS	Median	All	0.299	0.477	<.001	42	view →
HNSC	OS	Quartile	IV	0.505	0.884	.002	36	view →
KIRC	DFS	Quartile	All	0.805	0.892	.008	35	view →
ACC	DFS	Median	All	0.235	0.765	<.001	33	view →
BLCA	OS	Tertile	All	0.362	0.703	.008	26	view →
UCEC	DFS	Median	IV	0.852	0.558	.012	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 30 lineages.

SLC39A13–MESO (OS)

Open the MESO breakdown →