SLC39A12

Across TCGA cell cohorts, SLC39A12 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC39A12-associated genes across cancer lineages are AMY1A, GMNC, and CCL15. Each is linked with SLC39A12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A12-to-partner and partner-to-SLC39A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMY1A grouped by SLC39A12-low versus SLC39A12-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A12→partner) and Y-score (partner→SLC39A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	AMY1A →	+0.049	+3.906	.003	.009	3	2
BLOOD_Myeloma	GMNC →	+0.007	+4.285	<.001	.003	3	1
BLOOD_Myeloma	CCL15 →	+0.234	+3.906	<.001	.009	3	1
LARGE_INTESTINE	MMP26 →	+0.052	+3.632	<.001	.003	3	1
LARGE_INTESTINE	C14orf180 →	+0.112	+4.155	.001	.003	3	1
BREAST	OR10K2 →	+0.063	+5.781	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

AMY1A by SLC39A12 expression — BLOOD_Myeloma

Explore this box plot interactively →