Across TCGA pan-cancer cohorts, SLC39A12-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated SLC39A12-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SLC39A12-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SLC39A12-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LGG show a favorable association.

KIRC, LUAD, and CESC are the cancer types where SLC39A12-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.447	0.668	<.001	82	view →
LUAD	DFS	Tertile	II,III,IV	0.774	0.213	.010	54	view →
CESC	OS	Tertile	IV	0.149	0.614	.002	36	view →
DLBC	OS	Tertile	III,IV	0.172	0.907	<.001	36	view →
KIRP	DFS	Tertile	II,III,IV	0.520	0.765	.002	36	view →
LGG	OS	Median	All	0.937	0.854	<.001	28	view →
UVM	OS	Tertile	All	0.613	0.871	.006	27	view →
SARC	DFS	Tertile	All	0.394	0.628	.007	27	view →
STAD	DFS	Tertile	IV	0.097	0.412	.008	21	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	18	view →
COAD	DFS	Tertile	IV	0.153	0.531	.018	18	view →
LUSC	DFS	Tertile	III,IV	0.079	0.751	.024	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration

Same gene, other analysis: SLC39A12-AS1 tumor-vs-normal RNA expression · all SLC39A12-AS1 data types