Across TCGA pan-cancer cohorts, SLC39A10 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SLC39A10 data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SLC39A10 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLC39A10 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

KIRC, LIHC, and UCEC are the cancer types where SLC39A10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.135	0.631	<.001	36	view →
LIHC	DFS	Median	III,IV	0.076	0.360	.001	24	view →
UCEC	DFS	Median	All	0.825	0.629	.010	14	view →
LUSC	OS	Median	IV	0.057	0.786	.008	12	view →
HNSC	DFS	Median	III,IV	1.000	0.291	.040	2	view →
SCLC	DFS	Median	All	1.000	0.399	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: SLC39A10 tumor-vs-normal RNA expression · all SLC39A10 data types