SLC39A10

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC39A10 mutation is significantly associated with the RNA expression of many other genes, with 6,048 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A10-associated genes across cancer lineages are NPLP1, CDCA2, and IGHD2-15. Each is linked with SLC39A10 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC39A10-to-partner and partner-to-SLC39A10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A10→partner) and Y-score (partner→SLC39A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READNPLP1 →+0.291+5.421<.001.00533
UCECCDCA2 →+0.901+2.280<.001<.00133
LIHCIGHD2-15 →+0.950+5.108<.001.00833
UCECDNAH3 →-0.514-2.813.001.00133
UCECREEP4 →+0.518+2.555<.001<.00133
UCECBSG →+0.299+1.966.004.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,048 associations by consensus.

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