Across TCGA patient cohorts, SLC39A10 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A10-associated genes across cancer lineages are PRDX1, ATM, and EGFR_pY1068. Each is linked with SLC39A10 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC39A10-to-partner and partner-to-SLC39A10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A10→partner) and Y-score (partner→SLC39A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRDX1 →	+0.157	+1.362	.014	.034	3	3
COAD	ATM →	-0.828	-3.321	<.001	.009	2	4
UCEC	EGFR_pY1068 →	-0.251	-1.893	.001	<.001	3	2
COAD	FASN →	+0.380	+3.330	.038	.005	3	2
UCEC	HER3_pY1289 →	+0.063	+1.874	.017	.049	3	2
UCEC	PCNA →	+0.280	+1.893	<.001	<.001	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Exploration

SLC39A10 survival (RNA) · tumor vs normal (RNA) · all SLC39A10 data types