SLC39A1

Across TCGA patient cohorts, SLC39A1 mutation is significantly associated with the RNA expression of many other genes, with 1,430 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A1-associated genes across cancer lineages are RPLP1P10, RNA5SP408, and RN7SKP221. Each is linked with SLC39A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A1-to-partner and partner-to-SLC39A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPLP1P10 grouped by SLC39A1-low versus SLC39A1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A1→partner) and Y-score (partner→SLC39A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPLP1P10 →	+0.118	+4.669	<.001	.007	3	2
UCEC	RNA5SP408 →	+0.328	+3.017	.002	.003	3	2
KIRC	RN7SKP221 →	+0.104	+8.025	<.001	.007	3	2
LUAD	RNU6-451P →	+0.706	+4.468	<.001	.002	3	2
BLCA	RPL39P31 →	+0.220	+4.314	<.001	.009	3	2
BLCA	RNU6-1292P →	+0.202	+4.859	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,430 associations by consensus.

RPLP1P10 by SLC39A1 expression — CESC

Explore this box plot interactively →