SLC38A4

Across TCGA cell cohorts, SLC38A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,243 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC38A4-associated GO terms across cancer lineages are L-alanine import across plasma membrane, L-alanine transmembrane transport, and Purine nucleoside triphosphate biosynthetic process. Each is linked with SLC38A4 in more than 12 cancer types. Because this analysis shows association rather than direction, both SLC38A4-to-partner and partner-to-SLC38A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-alanine import across plasma membrane grouped by SLC38A4-low versus SLC38A4-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A4→partner) and Y-score (partner→SLC38A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	L-alanine import across plasma membrane →	-0.219	-1.127	<.001	.002	3	13
LARGE_INTESTINE	L-alanine transmembrane transport →	-0.218	-1.182	<.001	.001	3	11
BLOOD_Lymphoma	Purine nucleoside triphosphate biosynthetic process →	+0.062	+0.110	<.001	.003	3	5
BLOOD_Lymphoma	Purine ribonucleoside triphosphate biosynthetic process →	+0.062	+0.110	<.001	.003	3	5
UPPER_AERODIGESTIVE_TRACT	Regulation of actin filament organization →	+0.053	+1.294	.005	.002	3	5
OVARY	Negative regulation of lymphocyte migration →	-0.102	-0.735	.004	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,243 associations by consensus.

L-alanine import across plasma membrane by SLC38A4 expression — PANCREAS

Explore this box plot interactively →