SLC38A4

Across TCGA cell cohorts, SLC38A4 mutation is significantly associated with the drug of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC38A4-associated genes across cancer lineages are 50869, 150412, and 776928. Each is linked with SLC38A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC38A4-to-partner and partner-to-SLC38A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 50869 grouped by SLC38A4-low versus SLC38A4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A4→partner) and Y-score (partner→SLC38A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	50869 →	+0.536	+2.871	.006	.021	3	1
LARGE_INTESTINE	150412 →	+0.385	+3.000	.015	.017	3	1
LARGE_INTESTINE	776928 →	+0.603	+2.871	.045	.021	3	1
LARGE_INTESTINE	Savolitinib →	+0.403	+2.678	.024	.037	3	1
LARGE_INTESTINE	alpha-lipoic acid →	+0.333	+2.684	.020	.035	3	1
LARGE_INTESTINE	Oxaliplatin →	+0.527	+2.871	.035	.021	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

50869 by SLC38A4 expression — LARGE_INTESTINE

Explore this box plot interactively →